Neishay Ayub, MD: Stratifying SUDEP Risk Pubblicato il 16 gen 2019 Using the massive SeizureTracker database, Neishay Ayub, MD, and her colleagues sought to identify a way to stratify patients into risk groups and assess the way this risk changes over time.
To do so, they grouped patients with epilepsy into 1 of 3 cohorts based on their risk of sudden unexpected death in epilepsy (SUDEP). The low-risk group consisted of those with no generalized tonic-clonic seizures in a year, the medium-risk group was made up of those who had 1 to 2 of these seizures in a year, and the high-risk group was defined as those who had 3 or more of these seizures in a year.
Ultimately, they found that the length of time patients spent within their original group was significantly different between high- and low-risk groups (P .01) as well as between the medium- and low-risj groups (P .01). Although, there was no significant difference between the medium- and high-risk groups (P = .09).
To discuss the implications of these findings and what Ayub and her colleagues learned, the Clinical Fellow in Neurophysiology and Epilepsy at Massachusetts General Hospital sat down with NeurologyLive while on-site at the American Epilepsy Society’s annual meeting in New Orleans, Louisiana.
